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鏂板啝XBB鐨勬柊鍔犲潯缁忛獙锛氬啀鎰熸煋椋庨櫓楂橈紝姣掓€т綆锛岀柅鑻楀
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鍥? 2020骞?鏈?2023骞?鏈堬紝鏂板姞鍧℃柊鍐犲彉浣撶梾渚嬫暟鎹紙鍥炬簮锛氭柊鍔犲潯鍗敓閮級

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鍥? XBB绯荤粺杩涘寲鍒嗘瀽锛堝浘婧愶細[2]锛?/i>

01

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02

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03

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鍥? 鏂板啝鍙樹綋BQ鍜孹BB瀵规姉浣撶殑瓒呭己閫冮伩锛堝浘婧愶細[4]锛?/i>

04

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涓栧崼缁勭粐鏂板啝鎶€鏈礋璐d汉Maria Van Kerkhove鍗氬+鍦ㄦ湰鍛ㄤ笁鐨勬柊闂诲彂甯冧細涓婅锛氣€?strong>鎴戜滑瀵筙BB绯诲垪鐨勮秴寮轰紶鎾劅鏌撹兘鍔涙劅鍒版媴蹇э紝杩欑鐥呮瘨浼犳挱寰楄秺澶氾紝瀹冩敼鍙樼殑鏈轰細灏辫秺澶氥€俋BB.1.5鏄縿浠婁负姝㈡渶鍏蜂紶鎾€х殑鏂板啝鐥呮瘨鍙樼锛屼絾娌℃湁杩硅薄琛ㄦ槑瀹冩瘮浠ュ墠鐨勪富瑕佸彉绉嶆洿鑷村懡锛屼笌鍏剁鍏圤micron鑿屾牚涓€鏍锋俯鍜岋紝缇庡浗涓滃寳閮ㄧ殑鎰熸煋鍦板尯灏氭湭璁板綍浣忛櫌浜烘暟鐨勪笂鍗囥€?/strong>涓庡叾绁栧厛姣掓牚鐩告瘮锛孹BB.1.5鐥呮瘨鐨勫埡绐佽泲鐧藉彂鐢熶簡14绉嶆柊绐佸彉锛屽寮轰簡瀹冪殑鎶椾綋鎶楁€с€傝繖鎰忓懗鐫€鎺ョ杩囩柅鑻楁垨浠ュ墠鎰熸煋杩囩殑浜烘洿瀹规槗鎰熸煋銆備絾鏄紝鎶椾綋鍙槸閽堝鏂板啝鐥呮瘨鏁翠綋鍏嶇柅鍙嶅簲鐨勪竴閮ㄥ垎锛孴缁嗚優绛夊叾浠栨姉鐥呮瘨鐗╄川涔熻捣鐫€鑷冲叧閲嶈鐨勪綔鐢ㄣ€傗€?/p>

棣欐腐澶у鐥呮瘨瀛﹀閲戜笢鐕曡〃绀猴細鈥?strong>XBB.1.5骞舵病鏈夊鑷寸編鍥芥劅鏌撱€佷綇闄㈡垨姝讳骸浜烘暟鏄捐憲澧炲姞銆俋BB.1.5甯︽潵鐨勬縺澧烇紙濡傛灉鏈夌殑璇濓級杩滃皬浜?022骞村垵鍙戠敓鐨勬縺澧炪€備笉蹇呰繃澶氭媴蹇冨叾姣掑姏鎴栦簩娆℃劅鏌撶殑鍚庢灉銆?/strong>鈥?/p>

琚玁ature璇勪负鈥?022骞村府鍔╁閫犵瀛?0澶т汉鐗┾€濅箣涓€鐨勫寳澶ф浌浜戦緳鏁欐巿琛ㄧず:鈥?strong>涓浗澶у鏁颁汉宸茬粡鎺ョ浜嗙鍏堟牚鐤嫍锛屽叾璇卞鐨勪綋娑擦厤鐤XBB杩欑omicron绐佸彉鏍嚑涔庢棤鏁堛€傛劅鏌揃A.5.2鎴朆F.7搴峰鍚庯紝浜轰綋浜х敓鐨勬姉浣撳XBB绛夋渶鏂板彉寮傛瘨鏍殑涓拰鑳藉姏杈冧綆銆傚彲浠ラ瑙侊紝鍦ㄤ腑鍥紹A.5.2鍜孊F.7鎰熸煋楂樺嘲娑堥€€鍚庯紝鍙兘浼氬嚭鐜扮敱BQ.1.1銆乆BB鎴栧叾浠栧厤鐤€冮€歌兘鍔涙洿寮虹殑姣掓牚椹卞姩鐨勬劅鏌撻珮宄般€?/strong>鈥?/p>

閽堝XBB鏄惁浼氬鑷磋偁閬撶柧鐥咃紝鍖椾含浣戝畨鍖婚櫌鍛煎惛涓庢劅鏌撶鏉庝緱鏇惧尰鐢熻〃绀猴細鈥?strong>浣滀负鏂板啝鐥呮瘨缁撳悎缁嗚優鐨勪富瑕佸彈浣擄紝ACE2闄や簡鍦ㄨ偤閮ㄨ〃杈惧锛屽湪鑲犻亾鐨勫惈閲忎篃杈冮珮銆傛柊鍐犵梾姣掑悇涓彉寮傛牚閮戒細鎰熸煋鑲犻亾绮樿啘缁嗚優锛屼絾鏄敱浜庝釜浣撳樊寮備細鍐冲畾鏄惁浼氬嚭鐜拌偁閬撲复搴婄棁鐘躲€傚浜庢渶杩戝彈鍒板叧娉ㄧ殑XBB鍙婂叾杩涘寲鍒嗘敮锛屽苟娌℃湁璇佹嵁琛ㄦ槑姣斿叾浠栨瘨鏍洿瀹规槗瀵艰嚧涓ラ噸鑵规郴鎴栧叾浠栬儍鑲犻亾涓村簥琛ㄧ幇銆?/strong>鈥?/p>

鎾版枃|鏂囩珵鎷?/p>

鎺掔増|涔旂淮閽?/p>

End

鍙傝€冭祫鏂欙細

[1]Ngiam, Jinghao Nicholas MBBS; Al-Mubaarak, Abdurrahmaan BSc; Maurer-Stroh, Sebastian PhD, et al. Does the COVID-19 XBB Omicron subvariant signal the beginning of the end of the pandemic? Singapore Medical Journal锛孌ecember 01, 2022. DOI: 10.4103/singaporemedj.SMJ-2022-180.

[2]Tomokazu Tamura , Jumpei Ito , Keiya Uriu , et al. Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants. bioRxiv 2022.12.27.521986; doi: https://doi.org/10.1101/2022.12.27.521986

[3]Uraki R, Ito M, Furusawa Y, et al. Humoral immune evasion of the omicron subvariants BQ.1.1 and XBB. Lancet Infect Dis. 2023 Jan;23(1):30-32. doi: 10.1016/S1473-3099(22)00816-7. Epub 2022 Dec 7. PMID: 36495917; PMCID: PMC9729000.

[4]Wang Q, Iketani S, Li Z, et al. Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants. Cell. 2022 Dec 14:S0092-8674(22)01531-8. doi: 10.1016/j.cell.2022.12.018. Epub ahead of print. PMID: 36580913; PMCID: PMC9747694.

[5]Imai M, Ito M, Kiso M, et al. Efficacy of Antiviral Agents against Omicron Subvariants BQ.1.1 and XBB. N Engl J Med. 2022 Dec 7:NEJMc2214302. doi: 10.1056/NEJMc2214302. Epub ahead of print. PMID: 36476720; PMCID: PMC9749618.

[6]https://covid.cdc.gov/covid-data-tracker/#variant-proportions

关键词:鏂板,啝,XBB,鐨勬,柊鍔,犲潯,缁忛,獙锛,氬啀,
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